All dependent lines must be indented:
def MakeOneFeedScript():
    z = 1
    CFeedList = [str("null")]*3 #Liste mit Länge der Feeds Erstellen
    # Listen Für 1. 2. 3. Post, usw,
    IFeedList = [] #Liste für Posttime des 1. posts pro feed
    IIFeedList = [] #Liste für Posttime des 2. posts pro feed
    IIIFeedList = [] #Liste für Posttime des 3. posts pro feed
    IVFeedList = [] #Liste für Posttime des 4. posts pro feed
    VFeedList = [] #Liste für Posttime des 5. posts pro feed
    VIFeedList = [] #Liste für Posttime des 6. posts pro feed
    for i in range(z): #Alle Daten aus Dateien Lesen
        s = "/usr/lib/Advanced-Feed/tmp/" + str(i)  #
The indentation level is important!
If Speicherort Speichern is a comment, it must be preceded by a comment character:
# Speicherort Speichern
f = open(s, "rb") #Öffnen
If those are part of the previous code, ….
    for i in range(z): #Alle Daten aus Dateien Lesen
        s = "/usr/lib/Advanced-Feed/tmp/" + str(i)  #
        # Speicherort Speichern
        f = open(s, "rb") #Öffnen
        ...
        (presumably do something with "f")
3
solved Python 3: “Expected an indent Block” in a comment