A few ways to do this.
String replace, as mentioned by Ashish.
$input = "-**abcd1234-*---";
$output = str_replace(array('-', '*'), '', $input);
echo $output;
If you have a large number of characters to strip though, maybe this would be a little easier.
$input = "-**abcd1234-*---";
$remove = "-*";
$output = str_replace(str_split($remove), '', $input);
echo $output;
And of course, you can use regex.
$input = "-**abcd1234-*---";
$output = preg_replace('/[*-]/', '', $input);
echo $output;
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solved preg_replace/string_replace symbol – or * to space