You just need to do:
$('li.something').unbind('click'); // to disable
To enable you need to rebind the function
$('li.something').bind('click', function() { ...
I don’t know what you want to do, but if you actually want to unbind/bind the event like an (on/off) then you should store the function and just pass it in the bind.
Like:
function foo(){ ... }
$('li.something').unbind('click'); // to disable
$('li.something').bind('click', foo);
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solved Onclick “li” enable and disable