As mentioned in the comments you have to modify your code like this.
res1 = input()
if res1 in ("hi", "hey", "hello", "sup", "Hey Joe"):
GE = ("I am Joe, Your New Personal Assintant. Nice to meet you.")
print(GE)
os.system("say '" + GE + "'")
You have confused the effect of in
and is
; so changing is
with in
in your initial code solves your problem.
solved I am not understanding, What’s wrong with my code?