[Solved] How to remove duplicate from string/mixed list

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I think this is what you are trying to achieve:

x = []
while True:
    data = input()
    if data.lower() == "done":
        break
    if data not in x:
        x.append(data)

Note the use of while True and break to avoid having two input calls.

Alternatively, use a set:

x = set()
while True:
    data = input()
    if data.lower() == "done":
        break
    x.add(data)
x = list(x)

This will quietly ignore attempts to add duplicates.

If you actually do want to allow the user to remove items from x by entering them a second time, you can add the else and use remove (for the list) or discard (for the set), e.g.:

x = set() # or []
while True:
    data = input()
    if data.lower() == "done":
        break
    if data in x:
        x.discard(data) # or .remove(data)
    else:
        x.add(data) # or .append(data)

solved How to remove duplicate from string/mixed list