This had been a bug in usbser.sys
and was fixed with the Windows 10 Update KB3124262
from 27.01.2016.
The Microsoft employee explained:
The COM port name in the HKLM\HARDWARE\DEVICEMAP\SERIALCOMM registry is not NULL terminated.
Because of Windows 10’s update policies this issue should not appear in the future anymore.
solved How come GetDefaultCommConfig fails on windows 10