I’m not sure if I understand your question correctly.
You maybe better off using a dict.
>>> testbank = {"question 1":["answer1a", "answer1b", "answer1c", "answer1d"],
... "question n":["answerna", "answernb", "answernc", "answernd"]}
>>> testbank['question 1']
['answer1a', 'answer1b', 'answer1c', 'answer1d']
>>> def validate(answer, question):
... if answer in testbank['question 1']:
... print 'Correct!'
... else:
... print 'Try again.'
...
>>> answer = "answer1a"
>>> validate(answer, 'question 1')
Correct!
>>> wrongansw = 'foobar'
>>> validate(wrongansw, 'question 1')
Try again.
=========================
In lieu of your update on the requirement, you can use list of lists.
>>> answers = [["answer1a", "answer1b", "answer1c", "answer1d"],["answerna", "answernb", "answernc", "answernd"]]
>>> questions = ['question1','questionn']
>>> def validate(a,q):
... if a in answers[questions.index('question1')]:
... print 'Correct'
... else:
... print 'Try again'
...
>>> validate('foobar','question1')
Try again
>>> validate('answer1a','question1')
Correct
>>> validate('answer1b','question1')
Correct
4
solved Python: How to use a similar operator to “or”/”in” in a list [closed]